5 research outputs found
An Infectious Vessel: The Nineteenth-Century Prostitute Undressed
This dissertation serves as a literary âundressingâ of the nineteenth-century prostitute. It examines representations of the prostitute as both a physical and moral vessel of infection. To do so, the dissertation analyses representations from the common streetwalker to the prestigious courtesan, in both French and English novels including: Nana and LâAssommoir by Emile Zola, Oliver Twist by Charles Dickens, The Crimson Petal and the White by Michel Faber, Mary Barton by Elizabeth Gaskell, Mrs Warrenâs Profession by George Bernard Shaw and La Dame aux Camelias by Alexandre Dumas Fils. The work analyses and deconstructs stereotypical depictions of the prostitute. It also examines societal anxieties concerning the prostituteâs status as an infectious vessel and source of contamination. Additionally, the work incorporates and examines artistic interpretations of the prostitute by French and English artists. The dissertation uses the aforementioned depictions to analyse how manipulation of external appearance disguised the prostituteâs true âinfectiousâ status. The work ascertains that clothing, body and behaviour were deliberately âdressedâ by the prostitute to convey respectability and morality. The dissertation establishes that this masquerade enabled the prostitute to avoid societal detection, condemnation and criminalization. It reveals that the prostitute was able to and did avoid any traits that revealed her true status. The work demonstrates that through the adoption of disguise, the prostitute was able to infiltrate and infect rigid social hierarchies. It analyses how societal corruption was made possible by deliberate adjustments to appearance and behaviour. The dissertation establishes that the prostitute could successfully mislead and corrupt ârespectableâ society through a calculated guise of moral decency
The Nineteenth-Century Female Sex Worker in Britain and France: The Representation of Stereotypes in Visual and Literary Cultures
This thesis examines the subversion of stereotypes by the nineteenth-century female sex worker in Britain and France in visual and literary cultures. It uncovers the methods working-class women employed to escape the legal, medical, and cultural restrictions which arose from the RĂ©gime des Moeurs, Solicitation Laws, Contagious Diseases Acts, and the Criminal Law Amendment Bill. I explore how sex workers could evade detection and criminalisation by evading stereotypes regarding their clothing, body, and behaviour. I argue the womenâs carefully considered identity became an unforeseen and overlooked source of contagion for a society that sought to criminalize and ostracize the sex worker as a conduit of vice and venereal disease. Section 1 explores how sex workers manipulated clothing to transgress social boundaries and avoid police detection. I investigate how and why sex workers were able to manipulate clothing to reclaim personal agency. The section evaluates how sex worker stereotypes became morally contagious toward the rest of society. Section 2 focuses on the sex workerâs body to determine how the women were able to avoid corporeal stereotypes surrounding their weight, skin, cosmetics, perfume, and hair. I examine how the body could be manipulated to meet physical ideals of femininity created by the middle and upper class. However, I also identify the limits of stereotype subversion particularly concerning the fate of the fictional sex worker and her untimely demise. Section 3 investigates the stereotypes surrounding sex workersâ behaviour focusing on their manners, habits, and titles. It reveals how sex workers were constantly performing whether they altered their habits, recited middle- and upper-class mannerisms, or improved their etiquette and education. I primarily focus on male representations of the female sex worker in British and French literature; British texts include Charles Dickensâs Oliver Twist (1838), William Thackerayâs Vanity Fair (1848), Elizabeth Gaskellâs Mary Barton (1848), George Gissingâs Workers in the Dawn (1880) and The Unclassed (1884), and George Bernard Shawâs Mrs Warrenâs Profession (1893). French texts include Ămile Zolaâs LâAssommoir (1877), Nana (1880), and The Ladiesâ Paradise (1883), Joris Karl Huysmansâs Marthe (1876), and Alexandre Dumas filsâ La Dame aux CamĂ©lias (1848). I also reference several short stories and novels by French and British authors, draw from contextual resources including courtesan memoirs, newspaper reports, medical essays and social commentaries, and artwork to demonstrate the prevalence of sex worker stereotypes. The thesis concludes by determining the extent to which sex workers could reclaim personal agency by subverting stereotypes
The Nineteenth-Century Sex Worker: Avoiding Surveillance, Stereotypes, and Scandal
"This is an Accepted Manuscript of a book chapter published by Routledge in [The Routledge handbook of Victorian scandals in literature and culture] on [date of publication], available online: http://www.routledge.com/The-Routledge-Handbook-of-Victorian-Scandals-in-Literature-and-Culture/Ayres-Maier/p/book/9781032259963âThe subject of female sex work was a source of scandal throughout the nineteenth century. This chapter explores the writing of two males who defied the conventional approach to the topic, publishing three controversial texts which presented the female sex worker in an unseen light. Initially, the chapter studies Williamâs Acton Prostitution Considered in its Social, Moral, and Sanitary Aspects (1857, 1870) as a concerted effort to suppress the subject of female sex work. Geary-Jones analyzes Actonâs deeply rooted beliefs surrounding the working-class sex worker, investigating his traditional narratives that advocated and then supported the regulation of female sex work during the first and second editions of his publication. In particular, Geary-Jones examines the physicianâs attack against a series of sex worker stereotypes which had been firmly embedded in cultural ideology since the beginning of the century. These stereotypes come under scrutiny in George Gissingâs Workers in the Dawn (1880) and The Unclassed (1884), demonstrating the authorâs defiance of any conventional approach to the topic of female sex work in both his novels and personal relationships, resulting in scandal. This analysis is positioned against the cultural impact of the Contagious Diseases Acts (1864, 1866, 1869) in England and Jeremy Benthamâs The Panopticon Writings (1791)
The Nineteenth-Century prostitute: how the sexual âotherâ reclaimed power through deliberate dressing
The paper argues that nineteenth-century prostitutes reclaimed power through deliberate dressing. It explores how the dominant social body in England relied on clothing as a means of identification. As the public gaze formed identity, dress supposedly betrayed class status and moral standing. The paper argues that clothing served as a preventative social tool as it was used to identify sexual âOthersâ. Exploring the social obsession with sexual categorization, it reviews the clothing stereotypes used to identify prostitutes. To escape condemnation, prostitutes avoided typecasts and assumed the guise of âmoralâ women. By misinforming the public gaze, they evaded the confines of their âdeviantâ status. Constructing their own identity through deliberate dressing, they reclaimed power from the dominant social body. Able to move undetected through âmoralâ hierarchies, they threatened the stability of the social order. To explore how stereotypes became embedded in cultural ideology; the paper draws upon streetwalker depictions from Oliver Twist (1838) by Charles Dickens and Mary Barton (1848) by Elizabeth
Gaskell. It examines how fashion journals and âmoralâ commentators also perpetuated typecasts. Although stereotypes pertaining to prostitutes have been identified by scholars, they have overlooked how streetwalkers exploited this practice. Ultimately, the paper demonstrates how clothing stereotypes have been used by sexual âOthersâ to subvert identity. It reveals how individuals can disrupt the power of the dominant social body through deliberate dressing. Although this study focuses on nineteenth-century prostitutes, the argument can be applied to any era. As dress is used to construct identity, the process of stereotyping can be manipulated for personal gain
Whole-genome sequencing reveals host factors underlying critical COVID-19
Altres ajuts: Department of Health and Social Care (DHSC); Illumina; LifeArc; Medical Research Council (MRC); UKRI; Sepsis Research (the Fiona Elizabeth Agnew Trust); the Intensive Care Society, Wellcome Trust Senior Research Fellowship (223164/Z/21/Z); BBSRC Institute Program Support Grant to the Roslin Institute (BBS/E/D/20002172, BBS/E/D/10002070, BBS/E/D/30002275); UKRI grants (MC_PC_20004, MC_PC_19025, MC_PC_1905, MRNO2995X/1); UK Research and Innovation (MC_PC_20029); the Wellcome PhD training fellowship for clinicians (204979/Z/16/Z); the Edinburgh Clinical Academic Track (ECAT) programme; the National Institute for Health Research, the Wellcome Trust; the MRC; Cancer Research UK; the DHSC; NHS England; the Smilow family; the National Center for Advancing Translational Sciences of the National Institutes of Health (CTSA award number UL1TR001878); the Perelman School of Medicine at the University of Pennsylvania; National Institute on Aging (NIA U01AG009740); the National Institute on Aging (RC2 AG036495, RC4 AG039029); the Common Fund of the Office of the Director of the National Institutes of Health; NCI; NHGRI; NHLBI; NIDA; NIMH; NINDS.Critical COVID-19 is caused by immune-mediated inflammatory lung injury. Host genetic variation influences the development of illness requiring critical care or hospitalization after infection with SARS-CoV-2. The GenOMICC (Genetics of Mortality in Critical Care) study enables the comparison of genomes from individuals who are critically ill with those of population controls to find underlying disease mechanisms. Here we use whole-genome sequencing in 7,491 critically ill individuals compared with 48,400 controls to discover and replicate 23 independent variants that significantly predispose to critical COVID-19. We identify 16 new independent associations, including variants within genes that are involved in interferon signalling (IL10RB and PLSCR1), leucocyte differentiation (BCL11A) and blood-type antigen secretor status (FUT2). Using transcriptome-wide association and colocalization to infer the effect of gene expression on disease severity, we find evidence that implicates multiple genes-including reduced expression of a membrane flippase (ATP11A), and increased expression of a mucin (MUC1)-in critical disease. Mendelian randomization provides evidence in support of causal roles for myeloid cell adhesion molecules (SELE, ICAM5 and CD209) and the coagulation factor F8, all of which are potentially druggable targets. Our results are broadly consistent with a multi-component model of COVID-19 pathophysiology, in which at least two distinct mechanisms can predispose to life-threatening disease: failure to control viral replication; or an enhanced tendency towards pulmonary inflammation and intravascular coagulation. We show that comparison between cases of critical illness and population controls is highly efficient for the detection of therapeutically relevant mechanisms of disease